Processing of Insulin Crystals

Sterile Liquid Processing

GEA produces and supplies process systems for the production of liquid products for the pharmaceutical and biotechnological industries, and has a proven history of successfully installing plant for the production of insulin, including the engineering, delivery, commissioning and qualification of entire ultra-pure media systems as well as various process equipment and cleaning installations.

Insulin Production

The biosynthetic production of human insulin is done using bacteria or yeast cells. Following fermentation, or the conversion of the chemical raw materials by the micro-organisms, the biomass is extracted (at a constant concentration) by a nozzle separator, washed, concentrated and finally precipitated to produce insulin crystals.

The GEA Advantage

A worldwide technology leader in insulin production, GEA is able to supply the clean utility systems and manage the integration of all the main processes, including fermentation, harvesting, chromatography, filtration and freeze drying.

Centrifuges and process lines provided by GEA have an established pedigree in the clarification, separation, classification, concentration and fractionation steps. Nozzle separators also play an important part in the production process. In addition, GEA equipment is used in the subsequent crystallization stages, including chamber separators and self-cleaning separators.

GEA is a single-source supplier of a variety of fermenters, media preparation, buffer storage, harvesting and cell rupture solutions, equipment for the purification and isolation of cells, separation (after both first and final crystallization), the production and distribution of water-for-injection (WFI), Clean-in-Place (CIP) solutions and freeze drying technologies, all of which can be installed and integrated into a state-of-the-art insulin production facility.

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Dear partners,

We would like to inform you that in the framework of preventive measures aimed at effectively addressing the spread of “Covid19” disease and in accordance with the National Public Health Organization guidelines (https://eody.gov.gr/), our company is committed to ensure public health, safety of its partners and employees. Therefore we have recommended the fulfillment of our employees' tasks through teleworking.

The duration of this measure is initially set from 17.03.2020 to 30.04.2020

The design provides full operation, but due to special conditions, delays in specific tasks or communication may occur.

Our company will strive to keep its operation uninterrupted and secure by serving its clientele in ways and timeframes that are judged possible.

We thank you for understanding and we remain at your disposal.


Αγαπητοί Συνεργάτες,

Θα θέλαμε να σας ενημερώσουμε ότι στο πλαίσιο μέτρων πρόληψης με σκοπό την αποτελεσματική αντιμετώπιση εξάπλωσης του κορωνοιού και σύμφωνα με τις οδηγίες υγιεινής & ασφάλειας που έχει ορίσει ο ΕΟΔΥ (https://eody.gov.gr/), η εταιρία μας για να διασφαλίσει τη δημόσια υγεία, την ασφάλεια των συνεργατών και των εργαζομένων της, συστήσαμε την εκπλήρωση των καθηκόντων των εργαζομένων μας, μέσω τηλεργασίας.

Η διάρκεια του συγκεκριμένου μέτρου ορίζεται αρχικά από τις 17.03.2020 έως τις 30.04.2020

Ο σχεδιασμός προβλέπει πλήρη λειτουργία, ωστόσο εξαιτίας των ειδικών συνθηκών, ενδέχεται να παρουσιαστούν καθυστερήσεις σε συγκεκριμένες εργασίες ή και στην επικοινωνία.

Η εταιρία μας θα προσπαθήσει να διατηρήσει αδιάληπτη και ασφαλή την λειτουργία της, εξυπηρετώντας το πελατολόγιο της με τρόπους και σε χρονικά πλαίσια που κρίνονται δυνατά.

Σας ευχαριστούμε για την κατανόηση και παραμένουμε στην διάθεση σας.